|Organelles|Not membrane-bound, smaller|Membrane-bound, more complex|
|Organization|Usually singlecelled|Often form multicellular organisms|
|Metabolism|May not need oxygen|Usually need oxygen|
## Cellular Organelles
### Cell Membrane
- Controls what substances enter/leave the cell selectively via various receptors/osmosis
- Allows nutrients to enter
- Allows waste products to leave
- Surrounds and holds other organelles in cell
- Interact with outside chemicals (e.g., hormones)
### Nucleus
- Holds deoxyribonucleic acid (DNA) in form of chromatin
- DNA is a double helix that make genes
- Genes are a complete set of instructions to make a complete product (typically proteins)
- Chromatin is DNA wrapped tightly in protein
- Chromosomes are even more tightly wrapped chromatin used in cell division only
- Surrounded by a double membrane
- Substances enter and exit the nucleus via nuclear pores
- Messenger RNA (mRNA) is encoded from DNA and sent to ribosomes to produce proteins
### Nucleolus
- Dense region of DNA located in the nucleus
- This area of DNA is specially for ribosomal DNA (rDNA)
- Produce "large" and "small" units of complete ribosomes, which either remain free or mix with endoplasmic reticulum, forming rough endoplasmic reticulum (RER)
- Is *not* surrounded by a membrane, literally is just same as rest of nucleus but denser