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fixing some many mistakes left by eggy, and making things clear, more detailed, and more in-depth.
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@ -40,28 +40,30 @@ A person contains roughly 100 trillion cells
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### Cell Membrane
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### Cell Membrane
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- Controls what substances enter/leave the cell selectively via various receptors/osmosis
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- Controls what substances **enter/leave** the cell selectively via various receptors/osmosis
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- Allows nutrients to enter
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- Allows **nutrients** to enter
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- Allows waste products to leave
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- Allows **waste products** to leave (removal of waste)
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- Surrounds and holds other organelles in cell
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- Surrounds and holds other organelles in cell
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- Interact with outside chemicals (e.g., hormones)
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- Interact with outside chemicals (e.g., hormones)
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- Must transport food (ATP), nutrients into the cell
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### Nucleus
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### Nucleus
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- Is the control center of the cell
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- Holds deoxyribonucleic acid (DNA) in form of `chromatin`
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- Holds deoxyribonucleic acid (DNA) in form of `chromatin`
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- DNA is a double helix containing genes
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- DNA is a double helix containing genes
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- `Genes` are a full set of instructions in DNA to make either RNA or a protein
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- `Genes` are a full set of instructions in DNA to make either RNA or a protein, they are **found** in the DNA
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- `Chromatin` is DNA wrapped tightly in protein
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- `Chromatin`: is DNA **wrapped tightly** in protein
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- `Chromosomes` are even more tightly wrapped chromatin used in cell division only
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- `Chromosomes`: are even more tightly wrapped `chromatin` used in cell division only, formed when `DNA` **condenses** in `mitosis`
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- Surrounded by a double membrane
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- Surrounded by a double membrane
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- Substances enter and exit the nucleus via nuclear pores
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- Substances enter and exit the nucleus via `nuclear pores`. `Nuclear pores` are holes in the membrane that allow `proteins` and `nucleic acids` into the `cytoplasm`
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- Messenger RNA (mRNA) is encoded from DNA and sent to `ribosomes` to produce proteins
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- Messenger RNA (mRNA) is encoded from DNA and sent to `ribosomes` to produce proteins
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- Humans have ~2 m of genes per cell per nucleus tightly wrapped
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- Humans have ~2 meters of genes per cell per nucleus tightly wrapped
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### Nucleolus
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### Nucleolus
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- Dense region of DNA located in the nucleus
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- Dense region of DNA located in the nucleus (codes `ribosomes`; enzyemes that make protein)
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- This area of DNA is specially for ribosomal DNA (rDNA), or DNA used to make ribosomes
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- This area of DNA is specially for ribosomal DNA (rDNA), or DNA used to make ribosomes
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- Produce "large" and "small" subunits of ribosomes, which either form complete ribosomes in cytosol or mix with endoplasmic reticulum, forming rough endoplasmic reticulum (RER)
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- Produce "large" and "small" subunits of `ribosomes`, which either form complete `ribosomes` in `cytosol` or mix with `endoplasmic reticulum`, forming `rough endoplasmic reticulum` (RER)
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### Cytoplasm & Cytosol
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### Cytoplasm & Cytosol
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- `Cytosol` is the fluid cells contain
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- `Cytosol` is the fluid cells contain
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@ -69,7 +71,7 @@ A person contains roughly 100 trillion cells
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- `Cytoplasm` is the `cytosol` along with everything in a cell, excluding the nucleus
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- `Cytoplasm` is the `cytosol` along with everything in a cell, excluding the nucleus
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## Endoplasmic Reticulum
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## Endoplasmic Reticulum
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- The endoplasmic reticulum is a network of tubules and flattened sacs with a "rough" appearance because of the presence of `ribosomes` on the surface
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- The endoplasmic reticulum is a network of `tubules` and **flattened sacs** with a <b>*rough*</b> appearance because of the presence of `ribosomes` on the surface
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- Network of tubules and flattened sacs
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- Network of tubules and flattened sacs
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- **Transports** proteins via cytoskeleton in vesicles
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- **Transports** proteins via cytoskeleton in vesicles
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@ -83,11 +85,11 @@ A person contains roughly 100 trillion cells
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- Folds, fixes and **modifies both newly-created and pre-existing proteins** somewhat like **proof-reading**
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- Folds, fixes and **modifies both newly-created and pre-existing proteins** somewhat like **proof-reading**
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## Specific to Smooth ER
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## Specific to Smooth ER
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- Does not synthesize proteins
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- **Does not** synthesize proteins
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- Appears "smooth" due to lack of `ribosomes`
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- Appears "smooth" due to lack of `ribosomes`
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- Located directly adjacent and attached to nucleus
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- Located directly adjacent and attached to nucleus
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- Synthesizes lipids (fats, e.g., cholesterol)
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- Synthesizes lipids (fats, e.g., cholesterol)
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- Metabolises carbohydrates
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- **Metabolises** carbohydrates
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## Golgi Apparatus
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## Golgi Apparatus
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- Also known as Golgi body, Golgi complex, etc.
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- Also known as Golgi body, Golgi complex, etc.
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@ -107,73 +109,100 @@ A person contains roughly 100 trillion cells
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- Processes glucose + oxygen gas to form carbon dioxide + adenosine triphosphate (ATP)
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- Processes glucose + oxygen gas to form carbon dioxide + adenosine triphosphate (ATP)
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- ATP allows proteins to do things (e.g., spend 1 ATP break 1 molecule)
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- ATP allows proteins to do things (e.g., spend 1 ATP break 1 molecule)
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- ATP cannot be stored
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- ATP cannot be stored
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- ATP is needed for daily function of the cell
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## Cytoskeleton
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## Cytoskeleton
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- Made of protein filaments
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- Made of **protein filaments**
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- Maintains and changes cell structure, much like a human skeleton + muscular system
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- **Maintains** and **changes** cell structure, much like a human skeleton + muscular system
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- Moves cells
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- Moves cells
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- Modifies and adjusts cell structure as needed
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- Modifies and adjusts cell structure as needed
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- Chemicals can travel along cytoskeleton, e.g., organelles, vesicles, etc.
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- Chemicals can travel along `cytoskeleton`, e.g., `organelles`, `vesicles`, etc.
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## Organelles specific to animal cells
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## Organelles specific to animal cells
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1. Centrioles and centrosomes
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2. Lysosomes
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### Centrioles and centrosomes
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### Centrioles and centrosomes
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- Made of same protein as cytoskeleton
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- Made of same protein as `cytoskeleton`
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- A centrosome is a pair of centrioles
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- Important to cell division in animal cells
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- Important to cell division in animal cells
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- Create cilia and flagella (e.g., small hair-like things that swipe dirt out of lungs and tails of sperm, respectively)
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- Create cilia and flagella (e.g., small hair-like things that swipe dirt out of lungs and tails of sperm, respectively)
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### Lysosomes
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### Lysosomes
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- Explained before.
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## Organelles specific to plant cells
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## Organelles specific to plant cells
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1. Cell wall
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2. Chloroplast
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3. Central Vacuole
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### Cell wall
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### Cell wall
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- Provides structure and prevents cell rupture
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- Provides **structure** and prevents **cell rupture**
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- Can be tough, flexible, and/or rigid
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- A more stronger, thicker, rigit version of the `cell membrane`
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- Made of cellulose (type of sugar)
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- Made of **cellulose** (type of sugar)
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- Also present in most bacteria, fungi, and protists
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- Also present in most bacteria, fungi, and protists
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- The antibotic **Penicillin** works by destroying the cell walls of bacteria, thereby killing the bateria
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### Chloroplast
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### Chloroplast
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- The `solar panel` of the plant cell
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- The **solar panel** of the plant cell
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- Conducts photosynthesis
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- Conducts **photosynthesis**
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- All chlorophyll is located in chloroplasts
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- All chlorophyll is located in chloroplasts
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- Looks green
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- Looks green
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- Parts of the plant that do not photosynthesize do not have chloroplasts
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### Central Vacuole
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### Central Vacuole
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- Extremely large, may take up to 90% of volume in cell
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- Extremely large, may take up to 90% of volume in cell
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- Contains water
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- Contains water
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- Maintains `turgor` pressure against cell wall (pushes against cell wall in all directions)
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- Maintains `turgor` pressure against cell wall (pushes against cell wall in all directions)
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- Maintains cell shape and resistance
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- Maintains cell shape and resistance
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- Plant cells that lack turgor pressure (e.g., celery left in fridge) become flaccid
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- Plant cells that lack **turgor pressure** (e.g., celery left in fridge) become **flaccid**
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## Cell division
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## Cell Division
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### Purpose
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#### Growth
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- Cells have maximum size before transportation of substances within cell becomes inefficient
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- Cells transport chemicals (e.g., nutrients) via `diffusion`
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#### Reproduction
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## Purpose
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- Single-cellular organisms reproduce via division asexually
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### 1. Reproduction
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- Single-cellular organisms reproduce via division **asexually**
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- Multicellular organisms reproduce via combining two germ cells ("sex cells") that contain half the DNA each of two organisms
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- Multicellular organisms reproduce via combining two germ cells ("sex cells") that contain half the DNA each of two organisms
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- This is sexual
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- This is **sexual**
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#### Repair
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### 2. Growth
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- Cells have maximum size before transportation of substances within cell becomes **inefficient**, due to **larger cells** decreasing efficiency of `diffusion`
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- Cells transport chemicals (e.g., nutrients) via `diffusion`, this **limits cell size**
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- The only way to maintain proper function and get bigger is to **add more cells**
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### 3. Repair
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- **Organisms need to repair cells to stay alive and maintain proper health**
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- Millions of cells are replaced everyday
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- Cells naturally die and need to be replaced
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- Cells naturally die and need to be replaced
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- e.g., red blood cells, hair cells, skin, injuries
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- e.g., red blood cells, hair cells, skin, injuries, broken bones
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### Cell cycle
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## Cell cycle
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- Interphase
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- **Interphase**
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- G1
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- **G1** (normal groth and function),
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- S
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- Prepare for cell divison
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- G2
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- Duplication of DNA **S**,
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- Mitosis
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- Duplication of organelles **G2**
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- **Mitosis**
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- Occurs only in eukaryotic cells
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- Occurs only in eukaryotic cells
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- Prophase
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- P-MAT: Prophase Prometaphase, Metaphase, Anaphase, Telophase Cytokinesis
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- Prometaphase
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- nuclear divison
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- Metaphase
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- **Cytokinesis**
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- Anaphase
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- **cell division**
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- Telophase
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- **G0**
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- Cytokinesis
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- G0
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- Cell no longer divides
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- Cell no longer divides
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- Outisde of cell cycle
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- Outisde of cell cycle
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### Mitosis
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- PMAT (prophase, metaphase, anaphase, telophase)
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## Cell Specialization
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- `Zygote`: A one-celled organism formed from the fertilization of an egg by a sperm cell
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- A cell's position in the `gastrula` (outer, middle, inner layer) will determine the fate of the cell, or its potiental.
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- (LOCATION LOCATION LOCAION!)
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### Stem Cells
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- They are an **unspecialized** cell that has the potential to become one of several types of cells.
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- After cell division, either both can become stem cells or one stays as a stem cell and the other becomes a specialized cell
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-
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