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Update Unit 2: Biology.md
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@ -51,7 +51,7 @@ A person contains roughly 100 trillion cells
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- Is the control center of the cell
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- Holds deoxyribonucleic acid (DNA) in form of `chromatin`
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- DNA is a double helix containing genes
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- `Genes`: any section of DNA that contain a full set full set of instructions make either RNA or a protein
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- `Genes`: any section of DNA that contains a full set of instructions to make either RNA or a protein, **found** in nucleus
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- `Chromatin`: is DNA **wrapped tightly** in protein
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- `Chromosomes`: are even more tightly wrapped `chromatin` used in cell division only, formed when `DNA` **condenses** in `mitosis`
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- Surrounded by a double membrane
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@ -62,7 +62,7 @@ A person contains roughly 100 trillion cells
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### Nucleolus
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- Dense region of DNA located in the nucleus
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- This area of DNA is specially for ribosomal DNA (rDNA), or DNA used to code `ribosomes`, organelles that assemble proteins
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- This area of DNA is specially for ribosomal DNA (rDNA), or DNA used to code `ribosomes`, enzymes that assemble proteins
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- Produce "large" and "small" subunits of `ribosomes`, which either form complete `ribosomes` in `cytosol` or mix with `endoplasmic reticulum`, forming `rough endoplasmic reticulum` (RER)
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### Cytoplasm & Cytosol
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@ -124,11 +124,8 @@ A person contains roughly 100 trillion cells
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### Centrosomes
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- Made of same protein as `cytoskeleton`
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- **Create and manipulate spindle* during mitosis in animal cells
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- One centrosome is a bound pair of two `centrioles`, one mother and one daughter centriole
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- Centrioles are present in very few types of plant cells
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- Centrioles **create** spindle during mitosis in both plant and animal cells
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- Centrioles do not manipulate spindle
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- Crucial to mitosis in animal cells
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- **Create and manipulate spindle fibres** during mitosis in animal cells
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### Lysosomes
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- Explained before.
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@ -207,27 +204,13 @@ A person contains roughly 100 trillion cells
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- `Centromere`: Proteins sticking sister chromatids
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- PMAT (prophase, metaphase, anaphase, telophase)
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- Division of the nucleus
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- Prophase
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- Chromatin condenses into two identical `sister chromatids` which condense into `chromosomes`
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- Happens to 23 pairs of chromosomes
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- Nuclear membrane dissolves
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- Centrosomes move to opposite ends (`poles`) of cell, creating `spindle fibres` that begin to attach to `centromeres` in animal cells
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- Cell wall organises spindle in plant cell
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- Metaphase
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- Chromosomes line up in centre of cell to ensure they divide evenly
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- Everything in prophase has completed
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- Anaphase
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- Centromere splits
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- Sister chromatids are pulled towards opposite sides of cell via shortening spindle fibres
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- Sister chromatids now called `daughter chromosomes`
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- Telophase
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- Effectively opposite of prophase
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- Nuclear membranes form across each of the two nuclei
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- Daughter chromosomes unwind into chromatin and are no longer visible
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- Nucleolus forms in each nucleus
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- Spindle fibres break apart
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- **Cytokinesis** usually begins in telophase
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- Cell starts to **cleave** (cell centre starts to pinch itself)
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| Phase | Diagram | Description |
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| :--- | :--- | :--- |
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| Prophase | | - Chromatin condenses into two identical `sister chromatids` which condense into `chromosomes` <br> - Happens to 23 pairs of chromosomes <br> - Nuclear membrane dissolves <br> - Centrosomes move to opposite ends (`poles`) of cell, creating `spindle fibres` that begin to attach to `centromeres` in animal cells |
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| Metaphase | | - Chromosomes line up in centre of cell to ensure they divide evenly <br> - Everything in prophase has completed (e.g., nuclear membrane has dissolved completely) |
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| Anaphase | | - Centromeres split, separating sister chromatids <br> - Sister chromatids are pulled towards opposite sides of cell via shortening spindle fibres <br> - Sister chromatids are now called `daughter chromomsomes` |
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| Telophase | | - Effectively opposite of prophase <br> - Nuclear membranes form across each of the two new nuclei <br> - Daughter chromosomes unwind into chromatin and are no longer visible <br> - Nucleolus forms in each nucleus <br> - Spindle fibres break apart <br> - **Cytokinesis** usually begins in telophase <br> - Cells starts to **cleave** (cell centre starts to pinch itself) |
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### Cytokinesis
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- Cell division
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